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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC2
All Species:
44.55
Human Site:
Y279
Identified Species:
70
UniProt:
P35250
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35250
NP_002905.2
354
39157
Y279
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Chimpanzee
Pan troglodytes
XP_001149874
354
39149
Y279
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Rhesus Macaque
Macaca mulatta
XP_001082511
352
38844
Y277
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Dog
Lupus familis
XP_546916
352
38707
Y277
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUK4
349
38706
Y274
D
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Rat
Rattus norvegicus
Q641W4
349
38638
Y274
D
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516769
407
45006
Y332
H
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Chicken
Gallus gallus
P53033
359
39688
Y284
N
A
N
I
D
E
A
Y
K
I
L
A
H
L
W
Frog
Xenopus laevis
NP_001084837
348
38438
Y274
N
A
N
I
D
E
A
Y
K
I
V
A
H
L
W
Zebra Danio
Brachydanio rerio
NP_001013344
349
39005
Y274
N
A
N
I
D
E
A
Y
K
I
I
E
Q
L
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P53034
331
37155
H256
H
C
A
A
N
D
I
H
K
A
Y
K
I
L
A
Honey Bee
Apis mellifera
XP_623937
350
39000
S276
F
C
T
E
G
N
I
S
K
A
Y
G
V
M
E
Nematode Worm
Caenorhab. elegans
P34429
368
41157
N282
D
P
S
K
K
C
M
N
T
I
Q
T
K
L
F
Sea Urchin
Strong. purpuratus
XP_790650
352
38724
Y276
E
A
D
I
D
K
A
Y
E
I
M
H
H
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40339
323
36131
V236
D
S
P
H
P
L
I
V
K
K
M
L
L
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
93.5
N.A.
92.3
91.5
N.A.
76.6
87.7
86.4
82.7
N.A.
68.9
67.2
35
71.1
Protein Similarity:
100
99.7
98.8
96.6
N.A.
95.4
94.9
N.A.
81.5
91.6
91.5
88.4
N.A.
79.6
78.8
51.6
85.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
100
93.3
80
N.A.
13.3
6.6
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
40
13.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
74
7
7
0
0
74
0
0
14
0
60
0
7
7
% A
% Cys:
0
14
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
27
0
7
0
74
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
7
0
67
0
0
7
0
0
7
0
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
14
0
0
7
0
0
0
7
0
0
0
7
67
0
0
% H
% Ile:
0
0
0
74
0
0
20
0
0
80
7
0
7
0
0
% I
% Lys:
0
0
0
7
7
7
0
0
87
7
0
7
7
0
0
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
54
7
7
80
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
14
0
0
14
0
% M
% Asn:
47
0
67
0
7
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
7
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
0
7
0
0
0
0
0
0
14
% S
% Thr:
0
0
7
0
0
0
0
0
7
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
14
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _